Some of the world's best companies have a significant presence here.
Fortune 100 companies like Amazon.com, Microsoft, Barnes & Noble, and Intuit, among others, all operate in the Greater Reno-Tahoe area. Below is a list of Fortune 100 companies that have a significant presence in the Greater Reno-Tahoe area:
| 1 Wal-Mart | 41 Wells Fargo | 78 New York Life |
| 3 General Motors | 43 United Parcel Service | 79 American Express |
| 6 General Electric | 46 Wachovia Corp | 81 Washington Mutual |
| 8 Citigroup | 49 Microsoft | 83 Delphi |
| 9 Bank of America | 55 Caterpillar | 90 Mass Mutual |
| 19 Cardinal Health | 57 Lockheed Martin | 91 Countrywide Financial |
| 20 Morgan Stanley | 63 PepsiCo | 93 International Paper |
| 22 Merril Lynch | 65 Sysco | 94 Coca-Cola |
| 27 AT&T | 67 Johnson Controls | 95 Liberty Mutual |
| 28 Boeing | 68 FedEx | 96 Raytheon |
| 29 AmerisourceBergen | 69 Honeywell International | 98 Deere |
| 31 State Farm | 71 Alcoa | 99 Merck |
| 39 Pfizer | 77 Cisco Systems |
Source: Fortune Magazine (April 2007)
